Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Synchronus Presentation of Earlystage Small Cell Carcinoma and Adenocarcinoma in the Same Lung Lobe
Yoshihiro KobashiMinoru FukudaKouichiro YoshidaNaoyuki MiyashitaYoshihito NikiMikio Oka
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JOURNAL OPEN ACCESS

2006 Volume 45 Issue 5 Pages 287-291

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Abstract

A 73yearold man with no symptoms was admitted to our hospital with a nodular shadow (>2 cm) in the left upper lung field on chest Xray. A histological diagnosis (small cell carcinoma) was obtained by bronchoscopic examination including a transbronchial lung biopsy (TBLB). The preoperative clinical staging was T1N0M0 (StageIA). After preoperative chemotherapy (CDDP + CPT11) was carried out, a nodule in the left S1+2 diminished remarkably, but a smaller nodule in the left S3 (>8 mm) remained unchanged. While the nodule in the left S1+2 (small cell carcinoma) had become completely necrotic by the time the final diagnosis was made after resection of the left upper lobe, histological diagnosis of the nodule in the left S3 revealed a well differentiated adenocarcinoma. Synchronous presentation of earlystage lung cancer consisting of small cell carcinoma and adenocarcinoma was identified in the same left upper division of the lung. Because there have been the few previous reports regarding cases of synchronous presentation of earlystage lung cancer in the same lung lobe, we also report on the clinical characteristics, thus adding this case to the five previously reported cases.

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© 2006 by The Japanese Society of Internal Medicine
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