Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ORIGINAL ARTICLES
Four Cases of Graves' Disease which Developed after Painful Hashimoto's Thyroiditis
Hidemi OhyeEijun NishiharaIchiro SasakiSumihisa KubotaShuji FukataNobuyuki AminoKanji KumaAkira Miyauchi
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JOURNALS OPEN ACCESS

2006 Volume 45 Issue 6 Pages 385-389

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Abstract

We report four cases of Graves' disease that developed after painful Hashimoto's thyroiditis. All were middle-aged women, who had high titers of anti-thyroid antibodies and thyrotoxicosis at the onset of painful Hashimoto's thyroiditis. After 2 to 7 years, they developed Graves' disease with positive antibody against the thyrotropin receptor. Their clinical courses of Graves' disease went favorably due to the treatment with antithyroid drug or radioactive iodine therapy. Painful Hashimoto's thyroiditis is an atypical variant of Hashimoto's thyroiditis and is one form of destructive thyroiditis. Thyroid damage due to painful Hashimoto's thyroiditis may be associated with the development of Graves' disease.

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© 2006 by The Japanese Society of Internal Medicine
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