Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Post-Colonoscopic Listeria Septicemia in Ulcerative Colitis during Immunosuppressive Therapy
Masaaki MinamiTadao HasegawaTakafumi AndoOsamu MaedaTeruko OhkuraMichio OhtaHidemi Goto
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JOURNALS OPEN ACCESS

2007 Volume 46 Issue 24 Pages 2023-2028

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Abstract

A 78-year-old man who had been diagnosed with ulcerative colitis was admitted because of uncontrolled severe, frequent, bloody diarrhea. He was treated with immunosuppressive therapy that included corticosteroid and azathioprine. Colonoscopy was used to assess disease activity. This revealed that the mucosa of his digestive tract from the rectum to the ileum was damaged. He developed a high-grade fever soon after colonoscopy. Blood culture demonstrated Listeria monocytogenes. Treatment was changed to intravenous ampicillin for 20 days. His general body symptoms, including the bloody diarrhea, improved after treatment. We assume that the colonoscopy induced Listeria monocytogenes septicemia through bacterial translocation in this patient.

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© 2007 by The Japanese Society of Internal Medicine
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