Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
PICTURES IN CLINICAL MEDICINES
Granulocytic Sarcoma with Orbit, Cauda Equina, Muscle and Peripheral Nerve Extension but without Bone Marrow Involvement
Yasuhiro ManabeYoshiyuki HamakawaKazutaka SunamiYasuyuki OhtaNobuhiko OmoriKoji Abe
Author information
JOURNALS OPEN ACCESS

2007 Volume 46 Issue 9 Pages 633-635

Details
Abstract

We report a very rare case of granulocytic sarcoma (GS) with muscle and peripheral nerve extension but without bone marrow involvement. A 53-year-old woman presented with sciatic pain and diplopia. Magnetic resonance imaging revealed bilateral orbital and cauda equina region tumors. The blood cell count, and bone marrow histology and cytology were normal. The characteristic cerebrospinal fluid (CSF) cytologic picture of CD14+, CD33+, CD4+, CD56+ and positive nonspecific erastase staining suggested the diagnosis of GS. The patient underwent intrathecal and systemic chemotherapy, as if she had acute myeloid leukemia (AML). This case emphasizes the value of CSF cytological examination and the use of an immunocytochemical marker.

Information related to the author
© 2007 by The Japanese Society of Internal Medicine
Previous article
feedback
Top