Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
An Unusal Case of Acute Brucellosis Presenting with Coombs-positive Autoimmune Hemolytic Anemia
Ismail SariIsmail KocyigitFevzi AltuntasLeylagul KaynarBulent Eser
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JOURNALS OPEN ACCESS

2008 Volume 47 Issue 11 Pages 1043-1045

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Abstract

Brucellosis can mimic several primary hematological diseases. Mild anemia and leukopenia have been frequently associated with acute brucellosis, but pancytopenia, thrombocytopenia, and hemolysis are less frequently seen. To our knowledge, brucellosis has not previously been described in association with coombs-positive autoimmune hemolytic anemia. Here, we report a case of acute brucellosis presenting with coombs-positive autoimmune hemolytic anemia. The patient responded well to short-term pulse corticosteroid therapy followed by antibrucellosis treatment. We suggest that Brucella infection may be the probable cause of the immune hemolytic anemia in this patient. Therefore, the differential diagnosis of coombs-positive autoimmune hemolytic anemia should include brucellosis, especially in areas where the disease is endemic.

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© 2008 by The Japanese Society of Internal Medicine
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