Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Recurrent Gastric Perforation as a Late Complication of Radiotherapy for Mucosa-Associated Lymphoid Tissue Lymphoma of the Stomach
Taiga OtsukaTakahiro NodaMasako YokooKazuo Ibaraki
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JOURNAL OPEN ACCESS

2008 Volume 47 Issue 15 Pages 1407-1409

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Abstract

Radiation therapy can be used to treat Helicobacter pylori-negative or eradication-refractory extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) of the stomach. We report a case of gastric perforation which occurred more than 1 year after the completion of radiotherapy for H. pylori eradication-refractory gastric MALT lymphoma, and then recurred shortly afterwards. This was considered to be a late complication of radiation toxicity. Although gastric perforation due to radiotherapy has been reported very rarely in the past, even in advanced disease, this case shows that perforation can develop in patients with superficial disease and can relapse.

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© 2008 by The Japanese Society of Internal Medicine
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