Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
CASE REPORTS
Neurosyphilis with Mesiotemporal Magnetic Resonance Imaging Abnormalities
Kiwa HamaHiroshi IshiguchiTomikimi TujiHideto MiwaTomoyoshi Kondo
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JOURNALS OPEN ACCESS

2008 Volume 47 Issue 20 Pages 1813-1817

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Abstract

We describe a patient with mesial temporal T2-weighted image hyperintensity on magnetic resonance imaging that mimicked paraneoplastic limbic encephalitis. The patient showed pupillary abnormalities suggestive of a diagnosis of neurosyphilis, and the diagnosis was supported by the results of a serum Treponema pallidum hemagglutination assay (TPHA) and cerebrospinal fluid examination. Making a diagnosis of neurosyphilis is occasionally difficult because of the variety of clinical and imaging findings. Appropriate diagnosis and commencing adequate treatment are needed for a good prognosis; thus, neurosyphilis should be included in the differential diagnosis of mesiotemporal magnetic resonance imaging abnormalities.

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© 2008 by The Japanese Society of Internal Medicine
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