Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Gastrointestinal Hemorrhage as the First Manifestation of Metastatic Extragonadal Choriocarcinoma
Tomoyoshi ShibuyaTaro OsadaTomohiro KodaniMariko HojoHiroaki SaitoHiroya UeyamaJunko KatoAkihito NagaharaMichiro OtakaTatsuo OgiharaKeiji NagaoMakoto FujimeSumio Watanabe
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JOURNALS OPEN ACCESS

2009 Volume 48 Issue 7 Pages 551-554

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Abstract

Although germ cell tumors are the most common malignancy in young men, extragonadal germ cell tumors are rare. Gastric metastasis presenting initially as upper gastrointestinal hemorrhage is also exceedingly rare. A 27-year-old man presented at our hospital with tarry stool. Gastric fiberscopy images revealed a bleeding gastric polypoid lesion in the anterior wall of the gastric body, from which a biopsy specimen was obtained. Histopathological analysis of the biopsy showed syncytiotrophoblast-like cells with multiple, large nuclei, consistent with choriocarcinoma. Based on these results, our diagnosis was extragonadal retroperitoneal germ cell tumor with gastric metastasis.

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© 2009 by The Japanese Society of Internal Medicine
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