Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Changes in Metabolic Syndrome and Its Components with Lifestyle Modification in Japanese Men
Nobuyuki MiyatakeMasafumi FujiiMotohiko MiyachiIzumi TabataSuzue TakeshiTomohiro HiraoTakeyuki Numata
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2010 Volume 49 Issue 4 Pages 261-265


Objective Changes in metabolic syndrome and its components with lifestyle modification were evaluated in Japanese men.
Methods We used data for 160 Japanese men (45.6±8.8 years) with a 1-year follow up. Anthropometric, blood examination and blood pressure measurements were evaluated. Metabolic syndrome was defined by using a criterion in Japan. All subjects were given instructions by well-trained medical staff on how to change their lifestyle.
Results With a 1-year follow-up, anthropometric parameters, blood pressure (BP), triglyceride and HDL cholesterol were significantly improved and the prevalence of metabolic syndrome was significantly reduced. The number of subjects with abdominal obesity at baseline and at follow-up was higher (81 men) than that of subjects with other components at baseline and at follow-up. Parameters at baseline were significantly correlated with changes in parameters for one year. With lifestyle modification, the level of 163 mmHg in systolic BP (SBP), 115 mmHg in diastolic BP (DBP), 226 mg/dL in triglyceride and 33 mg/dL in HDL cholesterol at baseline was estimated to improve to the level without medications with a 1-year follow up.
Conclusion Lifestyle modification is useful for improving metabolic syndrome and its components. However, items of metabolic syndrome were improved, even when the abdominal circumference was greater than the normal value for Japanese men.

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© 2010 by The Japanese Society of Internal Medicine
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