Detection of BCR-ABL-Positive Cells in the Colostrum of a Pregnant Patient with Chronic Myeloid Leukemia

Yuki Hiroshima; Katsushi Tajima; Yousuke Shiono; Ikuko Suzuki; Kei Kouno; Yuuichi Katou; Takeo Kato

doi:10.2169/internalmedicine.50.5785

CASE REPORTS

Detection of BCR-ABL-Positive Cells in the Colostrum of a Pregnant Patient with Chronic Myeloid Leukemia

Yuki Hiroshima, Katsushi Tajima, Yousuke Shiono, Ikuko Suzuki, Kei Kouno, Yuuichi Katou, Takeo Kato

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Keywords: chronic myeloid leukemia (CML), pregnancy, breast feeding, colostrum, BCR-ABL, cord blood

JOURNAL OPEN ACCESS

2011 Volume 50 Issue 20 Pages 2389-2391

DOI https://doi.org/10.2169/internalmedicine.50.5785

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Abstract

A 31-year-old pregnant woman was diagnosed with chronic-phase chronic myeloid leukemia at gestational week 16. To avoid exposure of the fetus to teratogenic agents, the patient opted for a course of careful observation only for the duration of her pregnancy. We detected 9.1% of BCR-ABL-positive cells in the patient's colostrum with fluorescence in situ hybridization.

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