A Case of Adult T Cell Leukemia/Lymphoma Presenting as Severe Tracheal Stenosis

Kengo Otsuka; Koji Kuronuma; Mitsuo Otsuka; Junya Kitada; Yoshifumi Narita; Hirotoshi Homma; Satsuki Miyajima; Yasuo Kitamura; Yosuke Suzuki; Motoki Natsuizaka; Hiroshi Yasui; Hiroshi Ikeda; Toshiaki Hayashi; Tadao Ishida; Yasuhisa Shinomura; Hiroko Noguchi; Hiroki Takahashi

doi:10.2169/internalmedicine.50.5930

CASE REPORTS

A Case of Adult T Cell Leukemia/Lymphoma Presenting as Severe Tracheal Stenosis

Kengo Otsuka, Koji Kuronuma, Mitsuo Otsuka, Junya Kitada, Yoshifumi Narita, Hirotoshi Homma, Satsuki Miyajima, Yasuo Kitamura, Yosuke Suzuki, Motoki Natsuizaka, Hiroshi Yasui, Hiroshi Ikeda, Toshiaki Hayashi, Tadao Ishida, Yasuhisa Shinomura, Hiroko Noguchi, Hiroki Takahashi

Author information

Kengo Otsuka
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Koji Kuronuma
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Mitsuo Otsuka
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Junya Kitada
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Yoshifumi Narita
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Hirotoshi Homma
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Satsuki Miyajima
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Yasuo Kitamura
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Yosuke Suzuki
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Motoki Natsuizaka
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Hiroshi Yasui
Regional Health Care and Medicine, Sapporo Medical University School of Medicine, Japan
The First Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Hiroshi Ikeda
The First Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Toshiaki Hayashi
The First Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Tadao Ishida
The First Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Yasuhisa Shinomura
The First Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan
Hiroko Noguchi
Department of Surgical Pathology, Sapporo Medical University School of Medicine, Japan
Hiroki Takahashi
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan

Keywords: T cell lymphoma, tracheal stenosis, endobronchial imvolvement, ATLL

JOURNAL OPEN ACCESS

2011 Volume 50 Issue 21 Pages 2637-2641

DOI https://doi.org/10.2169/internalmedicine.50.5930

Details

Abstract

A 57-year-old woman was referred to our hospital for further examination of a tracheal stenosis shown on computed tomography findings. Bronchoscopy revealed multiple protruding tumors in the lumen of the trachea. Cytological findings of the cell block material from pleural effusion indicated that the T-cell lymphoma was composed of pleomorphic lymphoid cells. Serum human T-cell leukemia virus type1 antibody was positive and supported the clinical diagnosis of ATLL. Systemic chemotherapy induced the remarkable improvement of the lesions, the infiltrative lung shadow and the soft tissue neoplasm. We report a rare case of adult T cell leukemia/lymphoma (ATLL) with endobronchial involvement.

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