Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
A Case of Idiopathic Systemic Capillary Leak Syndrome with High Serum Levels of G-CSF on Exacerbation
Naoki NakagawaHisanobu OtaYasuko TanabeMaki KabaraMotoki MatsukiJunko ChindaNaka SakamotoTakayuki FujinoNaofumi TakeharaToshiharu TakeuchiJun-ichi KawabeNobuyuki SatoYuichiro KawamuraTakashi FukuharaKatsuya IkutaKenjiro KikuchiNaoyuki Hasebe
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JOURNALS OPEN ACCESS

2011 Volume 50 Issue 6 Pages 597-600

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Abstract

Systemic capillary leak syndrome (SCLS) is a life-threatening disorder which presents with periodic episodes of hypovolemic shock, due to plasma leakage to the extra-vascular space reflected by accompanying hypoalbuminemia, hemoconcentration and edema often with associated monoclonal gammopathy. We describe a 28-year-old woman with SCLS who required aggressive fluid resuscitation and was successfully treated with corticosteroid, terbutaline, and theophylline. At exacerbation, the levels of serum granulocyte colony-stimulating factor (G-CSF) were increased. Thus, G-CSF might play an important role and can be a useful biomarker for the severity of attacks in SCLS.

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© 2011 by The Japanese Society of Internal Medicine
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