Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Successful Remission of Evans Syndrome Associated with Graves' Disease by Using Propylthiouracil Monotherapy
Takashi UshikiMasayoshi MasukoKoji NikkuniJun Terukina-YoshidaAyako Momotsu-NanbaHiroshi MorikawaAkio UsamiIchiro FuseKen TobaKazue TakaiYoshifusa Aizawa
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JOURNALS OPEN ACCESS

2011 Volume 50 Issue 6 Pages 621-625

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Abstract

A 46-year-old woman with Graves' disease was admitted for anemia and thrombocytopenia. She had previously been treated with methimazole but she self-discontinued the treatment 6 months prior to admission. She was diagnosed with Evans syndrome associated with Graves' disease and treated with propylthiouracil without corticosteroids, which normalized her thyroglobulin level. Surprisingly, while Evans syndrome is characterized by frequent relapses, this patient has been in remission of Evans syndrome for approximately 4 years. The remission of Evans syndrome associated with Graves' disease in the absence of immunosuppressive therapy suggests that these 2 diseases have a common pathogenetic mechanism.

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© 2011 by The Japanese Society of Internal Medicine
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