Mediastinal Lymphadenopathy without Cervical Lymphadenopathy in a Case of Kikuchi- Fujimoto Disease

Yasushi Yoshida; Yasuo Matsuzawa; Hagino Rikitake; Toru Wakabayashi; Noriaki Okada; Toshihisa Kuroda; Kengo Kawashima; Masaaki Tanabe; Nobuyuki Hiruta; Makoto Nagashima; Tatsuo Kawashima

doi:10.2169/internalmedicine.50.4693

CASE REPORTS

Mediastinal Lymphadenopathy without Cervical Lymphadenopathy in a Case of Kikuchi- Fujimoto Disease

Yasushi Yoshida, Yasuo Matsuzawa, Hagino Rikitake, Toru Wakabayashi, Noriaki Okada, Toshihisa Kuroda, Kengo Kawashima, Masaaki Tanabe, Nobuyuki Hiruta, Makoto Nagashima, Tatsuo Kawashima

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Keywords: Kikuchi-Fujimoto disease, mediastinal lymph node, malignant lymphoma PET-CT

JOURNAL OPEN ACCESS

2011 Volume 50 Issue 6 Pages 649-652

DOI https://doi.org/10.2169/internalmedicine.50.4693

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Abstract

A 44-year-old man was referred to our hospital because of persistent high fever. Both CT and PET-CT demonstrated lymph node lesions limited to the mediastinal region without cervical lymphadenopathy. Histology of a mediastinal lymph node obtained by video-assisted thoroscopic excision confirmed the diagnosis of histiocytic necrotizing lymphadenitis. To our knowledge, this is the first report of Kikuchi-Fujimoto disease with isolated mediastinal lymphadenopathy. Although Kikuchi-Fujimoto disease is rare, we should consider this disease in patients with a high fever and no other symptoms.

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