Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Diffuse Large B-Cell Lymphoma Carrying both t(3 ; 7)(q27 ; p12) and t(8 ; 14)(q24 ; q32)
Yukitaka KatsuraIkuyo OhtaChikashi YoshidaHaruo OhtaniTakuya Komeno
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JOURNALS OPEN ACCESS

2011 Volume 50 Issue 8 Pages 905-908

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Abstract

We report a 60-year-old man with diffuse large B-cell lymphoma harboring both t(3 ; 7)(q27 ; p12) and t(8 ; 14)(q24 ; q32). Although he received six courses of conventional combination chemotherapy plus rituximab, early relapse occurred. Four courses of an intensive salvage regimen and high-dose chemotherapy with autologous peripheral blood stem cell transplantation were performed. The patient has remained in complete remission for over 24 months. This case is noteworthy because both genetic abnormalities are implicated in lymphomagenesis.

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© 2011 by The Japanese Society of Internal Medicine
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