Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Successful Treatment of Adult Onset Langerhans Cell Histiocytosis with Multi-Drug Combination Therapy
Eri MatsukiYuiko TsukadaAya NakayaKenji YokoyamaShinichiro Okamoto
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JOURNALS OPEN ACCESS

2011 Volume 50 Issue 8 Pages 909-914

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Abstract

Adult onset Langerhans cell histiocytosis (LCH) is a rare disorder. Its clinical features have been well described in children, however remain poorly defined in adults. Optimal treatment strategy is still under debate. We have encountered two cases of adult onset LCH, which obtained a durable disease control by combination chemotherapy using prednisone, vinblastine and 6-mercaptopurine. Herein, we report their clinical features together with a review of the current literature.

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© 2011 by The Japanese Society of Internal Medicine
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