Two Cases of Cerebral Embolism Caused by Apical Thrombi in Midventricular Obstructive Cardiomyopathy

Ikuko Takeda; Mayu Sekine; Hayato Matsushima; Naohisa Hosomi; Takeshi Nakamura; Toshiho Ohtsuki; Takemori Yamawaki; Masayasu Matsumoto

doi:10.2169/internalmedicine.50.5079

CASE REPORTS

Two Cases of Cerebral Embolism Caused by Apical Thrombi in Midventricular Obstructive Cardiomyopathy

Ikuko Takeda, Mayu Sekine, Hayato Matsushima, Naohisa Hosomi, Takeshi Nakamura, Toshiho Ohtsuki, Takemori Yamawaki, Masayasu Matsumoto

Author information

Ikuko Takeda
Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences, Japan
Mayu Sekine
Department of Neurology, Tokyo Saiseikai Central Hospital, Japan
Hayato Matsushima
Cerebrovascular Division, National Cerebral and Cardiovascular Center, Japan
Naohisa Hosomi
Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences, Japan
Takeshi Nakamura
Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences, Japan
Toshiho Ohtsuki
Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences, Japan
Takemori Yamawaki
Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences, Japan
Masayasu Matsumoto
Department of Clinical Neuroscience and Therapeutics, Hiroshima University, Graduate School of Biomedical Sciences, Japan

Keywords: cerebrovascular disease/stroke, midventricular obstructive cardiomyopathy, apical thrombus

JOURNAL OPEN ACCESS

2011 Volume 50 Issue 9 Pages 1059-1060

DOI https://doi.org/10.2169/internalmedicine.50.5079

Details

Abstract

Midventricular obstructive hypertrophic cardiomyopathy (MOHC) is a rare form of cardiomyopathy that was demonstrated to have caused embolic stroke in two patients. In both cases, the embolic sources of stroke were thrombi in an apical aneurysm caused by turbulent stasis of blood flow and subsequent injury of myocardial endocardium. Even without atrial fibrillation, apical aneurysm can induce emboligenic stroke in MOHC.

Corresponding author

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