Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
CASE REPORTS
Sarcoidosis Manifesting as Cardiac Sarcoidosis and Massive Splenomegaly
Sayaka KawanoJohji KatoNoriaki KawanoYuki YoshimuraHiroyuki MasuyamaTakashi FukunagaYoshiya ShimaoKenroh MiharaAkira UedaKiyokazu ToyodaTakuroh ImamuraKazuo Kitamura
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JOURNALS OPEN ACCESS

2012 Volume 51 Issue 1 Pages 65-69

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Abstract

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology. We report an unusual case of sarcoidosis in a woman presenting with cardiac sarcoidosis and massive splenomegaly with a familial history of cardiac sarcoidosis. Cardiac sarcoidosis was diagnosed based on electrocardiogram, echocardiogram, 18F-fluoro-2-deoxyglucose positron emission tomography (18F-FDG-PET) and skin histological findings. We performed splenectomy to rule out malignant lymphoma, and histological findings confirmed sarcoidosis. After splenectomy, we initiated prednisolone therapy. After 20 months of diagnosis, she was symptom free. Echocardiography and 18F-FDG-PET may be a key diagnostic tool and prednisolone therapy may be safe, effective, and feasible for cardiac sarcoidosis.

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© 2012 by The Japanese Society of Internal Medicine
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