Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
CASE REPORTS
A Case of Type 2 Diabetes and Metastatic Liver Cancer Exhibiting Hypercholesterolemia with Abnormal Lipoproteins
Motoko KanzakiJun WadaAtsuko NakatsukaSanae TeshigawaraKazutoshi MurakamiKentaro InoueTakahiro TeramiAkihiro KatayamaJunichiro NasuKazuhide YamamotoHirofumi Makino
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JOURNALS OPEN ACCESS

2012 Volume 51 Issue 6 Pages 619-623

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Abstract

Although the appearance of abnormal lipoproteins in liver diseases is well known, the precise analyses of abnormal lipoproteins remain elusive. Here, we report a 71-year-old woman with type 2 diabetes whose serum cholesterol levels were elevated to 560 mg/dL over a 4-month period. High-performance liquid chromatography demonstrated the presence of lipoprotein-X and lipoprotein-Y and sigmoid colon cancer and multiple liver metastases were found by colonoscopy and computed tomography. Remission of the primary colon cancer and liver lesions was achieved by chemotherapy with oxaliplatin and fluorouracil and her serum cholesterol went back to basal levels associated with the disappearance of abnormal lipoproteins.

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© 2012 by The Japanese Society of Internal Medicine
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