Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
A Case of Good Syndrome with Pulmonary Lesions Similar to Diffuse Panbronchiolitis
Takaaki OgoshiHiroshi IshimotoKazuhiro YateraKeishi OdaKentarou AkataKei YamasakiTakashi KidoToshinori KawanamiChiharu YoshiiHiroshi Mukae
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JOURNALS OPEN ACCESS

2012 Volume 51 Issue 9 Pages 1087-1091

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Abstract

We herein present a case of Good syndrome complicated by diffuse pulmonary lesions similar to diffuse panbronchiolitis (DPB). A 45-year-old Japanese man was referred to our department due to recurrent lower respiratory tract infections that had started and ameliorated nine months after thymectomy for pure red cell aplasia and myasthenia gravis. Diffuse centrilobular opacities on chest computed tomography and positivity for HLA-B54 were consistent with DPB. Additionally, hypogammaglobulinemia and a marked decrease of B-lymphocytes were observed, and therefore Good syndrome was considered. Combination therapy with azithromycin and clarithromycin alleviated the patient's respiratory symptoms and reduced the exacerbation of chronic bronchitis.

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© 2012 by The Japanese Society of Internal Medicine
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