Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Maintenance of the Remission Stage of Crohn's Disease with Adalimumab Therapy during Pregnancy
Tsutomu MizoshitaSatoshi TanidaHironobu TsukamotoKeiji OzekiTakahito KatanoMasahide EbiYoshinori MoriHiromi KataokaTakeshi KamiyaTakashi Joh
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JOURNAL OPEN ACCESS

2013 Volume 52 Issue 10 Pages 1049-1053

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Abstract

A 25-year-old pregnant woman complained of abdominal pain and diarrhea. Total colonoscopy provided a diagnosis of Crohn's disease (CD) of the large intestine (Crohn's colitis). Because the patient was allergic to mesalazine, adalimumab (ADA) was used as maintenance therapy during pregnancy, following prednisolone as remission induction therapy. Remission of the patient's CD was maintained with ADA, and the patient delivered a baby girl without any difficulties. Remission of the patient's CD continued to be maintained with the administration of ADA after childbirth. We believe that this is the first report of the use of ADA therapy in a pregnant CD patient in Japan.

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© 2013 by The Japanese Society of Internal Medicine
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