Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Spontaneous Remission in Patients with Acute Myeloid Leukemia with t(8;21) or Cutaneous Myeloid Sarcoma: Two Case Reports and a Review of the Literature
Qingchao ZengYan YuanPei LiTong Chen
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JOURNALS OPEN ACCESS

2013 Volume 52 Issue 11 Pages 1227-1233

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Abstract

Spontaneous remission (SR) in patients with acute myeloid leukemia (AML) is rare. We herein present two such cases. The first case was of AML-M2 accompanied by a bone marrow cytogenetic analysis revealing 46, XY, t(8;21)(q22,q22). The second case was of isolated cutaneous myeloid sarcoma (MS) that progressed to AML within seven months. Both of the patients had symptoms of infection and anemia and were therefore treated with antibiotics and transfusions. The SR lasted for two months and one month, respectively. Currently, the mechanisms underlying SR remain ambiguous. Possible underlying mechanisms with a review of the related literature are discussed.

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© 2013 by The Japanese Society of Internal Medicine
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