Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Pathological Evidence of the Cause of Spontaneous Regression in a Case of Resected Hepatocellular Carcinoma
Shunichi MatsuokaAkinori TamuraMitsuhiko MoriyamaHirotoshi FujikawaKenji MimatsuTakatsugu OidaMasahiko Sugitani
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JOURNAL OPEN ACCESS

2015 Volume 54 Issue 1 Pages 25-30

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Abstract

A 67-year-old man presented for an evaluation after experiencing right hypochondrial pain lasting for two months. Abdominal ultrasonography showed a hepatic tumor in the right liver and extremely mild hepatic steatosis. The imaging findings indicated that the tumor (43 mm in size) was ischemic, and the lesion was surgically resected and examined. The histopathological findings demonstrated 95% necrosis with moderately differentiated hepatocellular carcinoma (HCC). The diagnosis was HCC with spontaneous regression. There was also pathological evidence of thrombus formation in the peripheral arteries and portal veins. In addition, the non-cancerous regions of the liver were diagnosed as exhibiting non-alcoholic steatohepatitis. The pathological findings obtained after resection of the HCC lesion showed spontaneous regression.

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© 2015 by The Japanese Society of Internal Medicine
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