Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Corticoid Therapy for Overlapping Syndromes in an HIV-positive Patient
Yu KakuShoko KodamaMakiko HiguchiAkihiro NakamuraMasataka NakamuraTomoe KaiedaSoichiro TakahamaRumi MinamiTomoya MiyamuraEiichi SuematsuMasahiro Yamamoto
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JOURNAL OPEN ACCESS

2015 Volume 54 Issue 2 Pages 223-230

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Abstract

Human immunodeficiency virus (HIV) infection disturbs the host's immune function and often coexists with various autoimmune and/or systemic rheumatic diseases with manifestations that sometimes overlap with each other. We herein present the case of a 43-year-old Japanese man infected with HIV who exhibited elevated serum creatine kinase and transaminases levels without any symptoms. He was diagnosed with autoimmune hepatitis, polymyositis and Sjögren's syndrome and received combined antiretroviral therapy (cART); however, the laboratory abnormalities persisted. We successfully administered cART with the addition of oral prednisolone, and the patient's condition recovered without side effects related to the metabolic or immunosuppressive effects of these drugs.

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© 2015 by The Japanese Society of Internal Medicine
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