Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Late Metabolic Acidosis Caused by Renal Tubular Acidosis in Acute Salicylate Poisoning
Norihiro SakaiYasuo HiroseNobuhiro SatoDaisuke KondoYuko ShimadaYasushi Hori
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JOURNAL OPEN ACCESS

2016 Volume 55 Issue 10 Pages 1315-1317

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Abstract

A 16-year-old man was transferred to our emergency department seven hours after ingesting 486 aspirin tablets. His blood salicylate level was 83.7 mg/dL. He was treated with fluid resuscitation and sodium bicarbonate infusion, and his condition gradually improved, with a decline in the blood salicylate level. However, eight days after admission, he again reported nausea, a venous blood gas revealed metabolic acidosis with a normal anion gap. The blood salicylate level was undetectable, and a urinalysis showed glycosuria, proteinuria and elevated beta-2 microglobulin and n-acetyl glucosamine levels, with a normal urinary pH despite the acidosis. We diagnosed him with relapse of metabolic acidosis caused by renal tubular acidosis.

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© 2016 by The Japanese Society of Internal Medicine
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