Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Successful Treatment of Aspergillus Empyema Using Open Window Thoracostomy Salvage Treatment and the Local Administration of an Antifungal Agent
Nobuyuki AshizawaShigeki NakamuraShotaro IdeMasato TashiroTakahiro TakazonoYoshifumi ImamuraTaiga MiyazakiKoichi IzumikawaYoshihiro YamamotoKatsunori YanagiharaYoshitsugu MiyazakiShigeru Kohno
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JOURNAL OPEN ACCESS

2016 Volume 55 Issue 15 Pages 2093-2099

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Abstract

A 76-year-old woman received long-term immunosuppressive treatment for collagen vascular disease-associated interstitial pneumonia. The patient developed a cavitary mass lesion in the right lower lung field, and both nontuberculous mycobacteria and Aspergillus spp. were isolated after bronchial washing. The patient underwent a right lower lobectomy but developed Aspergillus empyema. Empyema due to Aspergillus spp. is a rare and life-threatening condition; however, the standard therapeutic strategies for treating Aspergillus empyema are not clear. We herein report a case of Aspergillus empyema that was successfully treated with a combination therapy which included open-window thoracostomy and the administration of antifungal agents (systemic micafungin and local amphotericin-B).

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© 2016 by The Japanese Society of Internal Medicine
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