Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
IgG4-related Disease with Bone Marrow Involvement
Akifumi IchikiNorisato HashimotoTomoki UedaShinichiro HiraiwaTakuma TajiriNaoya NakamuraKiyoshi AndoKenji Yokoyama
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JOURNALS OPEN ACCESS

2016 Volume 55 Issue 16 Pages 2295-2299

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Abstract

A 61-year-old Japanese woman with anemia, submandibular gland swelling, and enlarged lymph nodes was diagnosed with IgG4-related disease (IgG4-RD) by lymph node biopsy. Bone marrow involvement of IgG4-RD was detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) and immunohistochemically proven by bone marrow biopsy in this patient. Anemia progressed gradually, and prednisolone treatment was initiated. Anemia and submandibular gland swelling improved soon after prednisolone treatment was initiated. We report a rare case of IgG4-RD involving the bone marrow. FDG-PET/CT and bone marrow biopsy were useful for diagnosis in this case.

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© 2016 by The Japanese Society of Internal Medicine
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