Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Complete Remission of Minimal Change Disease Following an Improvement of Lung Mycobacterium avium Infection
Aoi YamashiroTakahiro UchidaSeigo ItoNaoki OshimaTakashi OdaHiroo Kumagai
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JOURNALS OPEN ACCESS

2016 Volume 55 Issue 18 Pages 2669-2672

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Abstract

A 46-year-old woman suddenly developed peripheral edema. Her massive proteinuria, hypoproteinemia, and renal biopsy findings yielded the diagnosis of minimal change disease (MCD). In addition, lung Mycobacterium avium infection was diagnosed according to a positive culture of her bronchoalveolar lavage fluid. The lung lesion was improved by anti-nontuberculous mycobacteria therapy. Surprisingly, her proteinuria also gradually decreased and she attained complete remission of MCD without any immunosuppressive therapy. She has subsequently remained in complete remission. We herein report an interesting case of MCD with lung Mycobacterium avium infection, suggesting a causal relationship among infection, immune system abnormality, and MCD/nephrotic syndrome.

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© 2016 by The Japanese Society of Internal Medicine
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