Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Cord Blood Transplantation Provided Long-term Remission in a Case of Adult T-cell Leukemia-lymphoma (ATL) with Myelofibrosis
Hidehiro ItonagaJun TaguchiTakeharu KatoShinya SatoYasushi SawayamaYoshitaka ImaizumiDaisuke NiinoTomoko HataTakuya FukushimaKoichi OhshimaYasushi Miyazaki
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JOURNALS OPEN ACCESS

2016 Volume 55 Issue 2 Pages 197-201

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Abstract

A 53-year-old man was diagnosed with adult T-cell leukemia-lymphoma (ATL) acute type transformed from chronic type. A bone marrow analysis showed diffuse infiltration of abnormal lymphocytes and diffuse fibrotic change. He received unrelated cord blood transplantation (CBT) following reduced-intensity conditioning with complete remission of ATL after two courses of chemotherapy and achieved neutrophil and platelet engraftment. At 99 days after CBT, a bone marrow biopsy showed apparent resolution of myelofibrosis. These results suggest the therapeutic potential of CBT for patients with chemosensitive ATL with myelofibrosis.

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© 2016 by The Japanese Society of Internal Medicine
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