Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Gastric Hyperplastic Polyps Associated with Proton Pump Inhibitor Use in a Case without a History of Helicobacter pylori Infection
Shuichi MiyamotoMototsugu KatoKana MatsudaSatoshi AbikoMomoko TsudaTakeshi MizushimaKeiko YamamotoShoko OnoTakahiko KudoYuichi ShimizuKanako C. HatanakaIzumi TsunematsuNaoya Sakamoto
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ジャーナル オープンアクセス

2017 年 56 巻 14 号 p. 1825-1829

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A 56-year-old man with gastroesophageal reflux disease (GERD) was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed no evidence of any polypoid lesions in the stomach, and the patient had no history of Helicobacter pylori infection. He received omeprazole (20 mg) once daily for the GERD. EGD was performed at 1 year after the start of omeprazole administration, and this time, gastric hyperplastic polyps (GHPs) were detected. The GHPs increased in size as the omeprazole treatment continued, but they markedly decreased in size following omeprazole discontinuation. Thus, the administration of proton pump inhibitors may be a risk factor for the development of GHP independent of H. pylori infection.

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© 2017 by The Japanese Society of Internal Medicine
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