Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Multicentric Reticulohistiocytosis with Dermatomyositis-like Eruptions
Natsuki ShimaTakamasa MurosakiTakao NagashimaMasahiro IwamotoYusuke AmanoNaomi NakanoMamitaro OhtsukiSeiji Minota
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JOURNAL OPEN ACCESS

2017 Volume 56 Issue 15 Pages 2063-2066

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Abstract

A 68-year-old man presented with polyarthritis, proximal muscle weakness, and erythema of the face, arms, neck, and anterior chest that resembled the V-neck sign. Initially, dermatomyositis (DM) was considered because of the erythema, polyarthritis, and muscle weakness. He also had mediastinal and hilar lymphadenopathy on contrast-enhanced computed tomography. Unexpectedly, a biopsy of the forehead skin revealed numerous multinucleated giant cells. A biopsy of a solitary nodule on the dorsum of his right middle finger revealed similar multinucleated giant cells with ground-glass cytoplasm, leading to the diagnosis of multicentric reticulohistiocytosis (MRH). Although MRH is rare, it should be remembered that MRH can mimic DM.

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© 2017 by The Japanese Society of Internal Medicine
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