Interstitial Lung Disease as an Initial Manifestation of Giant Cell Arteritis

Chisato Konishi; Kazuhiko Nakagawa; Erika Nakai; Kenta Nishi; Ryoichi Ishikawa; Shinya Uematsu; Satoshi Nakao; Masato Taki; Kyohei Morita; Hwang Moon Hee; Chie Yoshimura; Toshiaki Wakayama; Yasuo Nishizaka

doi:10.2169/internalmedicine.8861-17

CASE REPORTS

Interstitial Lung Disease as an Initial Manifestation of Giant Cell Arteritis

Chisato Konishi, Kazuhiko Nakagawa, Erika Nakai, Kenta Nishi, Ryoichi Ishikawa, Shinya Uematsu, Satoshi Nakao, Masato Taki, Kyohei Morita, Hwang Moon Hee, Chie Yoshimura, Toshiaki Wakayama, Yasuo Nishizaka

Author information

Chisato Konishi
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Kazuhiko Nakagawa
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Erika Nakai
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Kenta Nishi
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Ryoichi Ishikawa
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Shinya Uematsu
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Satoshi Nakao
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Masato Taki
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Kyohei Morita
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Hwang Moon Hee
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Chie Yoshimura
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Toshiaki Wakayama
Department of Pulmonology, Osaka Red Cross Hospital, Japan
Yasuo Nishizaka
Department of Pulmonology, Osaka Red Cross Hospital, Japan

Keywords: giant cell arteritis, interstitial lung disease, granulomatous ILD, ¹⁸F-FDG PET/CT, vasculitis-associated ILD

JOURNAL OPEN ACCESS

2017 Volume 56 Issue 19 Pages 2633-2637

DOI https://doi.org/10.2169/internalmedicine.8861-17

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Abstract

Interstitial lung disease (ILD) has rarely been reported as a manifestation of giant cell arteritis (GCA). We herein report a unique case of GCA in a 76-year-old woman who presented with ILD as an initial manifestation of GCA. Ten years before admission, she had been diagnosed with granulomatous ILD of unknown etiology. Corticosteroid therapy induced remission. One year after the cessation of corticosteroid therapy, she was admitted with a persistent fever. After admission, she developed left oculomotor paralysis. Positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose integrated with computed tomography (¹⁸F-FDG PET/CT) proved extremely useful in establishing the diagnosis. Our case promotes awareness of GCA as a possible diagnosis for granulomatous ILD with unknown etiology.

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