Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Deep Ulcers in the Ileum Associated with Mycophenolate Mofetil
Akira SonodaKurato WadaKazuhiro MizukamiKensuke FukudaMitsutaka ShutoKazuhisa OkamotoRyo OgawaTadayoshi OkimotoKazunari Murakami
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JOURNAL OPEN ACCESS

2017 Volume 56 Issue 21 Pages 2883-2886

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Abstract

A 54-year-old man was treated with mycophenolate mofetil (MMF) after undergoing living donor renal transplantation. Two years later, he experienced repeated episodes of diarrhea, and his C-reactive protein (CRP) level was found to be 12.63 mg/dL. Ileocolonoscopy showed multiple deep, punched-out ulcers that were similar to Behçet's disease (BD) and cytomegalovirus (CMV) in the ileum. CMV infection was suspected. However, anti-cytomegalovirus agents were ineffective. The patient was subsequently diagnosed with gastrointestinal toxicity of MMF and MMF was switched to mizoribine. His symptoms improved immediately, and his CRP level normalized. Six months later, the patient's mucosa was healed.

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© 2017 by The Japanese Society of Internal Medicine
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