Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Repeated Diffuse Alveolar Hemorrhage in a Patient with Hemophilia B
Hajime KasaiJiro TeradaHiromasa HoshiTakashi UrushibaraFumiaki KatoRintaro NishimuraKoichiro Tatsumi
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JOURNAL OPEN ACCESS

2017 Volume 56 Issue 4 Pages 425-428

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Abstract

Diffuse alveolar hemorrhage (DAH) is a life-threatening complication that occurs in association with various diseases including coagulation disorders. In rare cases, it is caused by hemophilia. A 48-year-old man was admitted to our hospital for a third time due to DAH. Although the cause of DAH could not be identified by bronchoscopy or laboratory tests, a good response to corticosteroids suggested idiopathic DAH with pulmonary capillaritis. The patient was diagnosed with hemophilia B based on the results of a detailed inquiry, a mildly prolonged activated partial thromboplastin time, and low factor IX activity. Hemophilia may be an underlying factor that exacerbates the bleeding of patients with DAH, even when they show a good response to corticosteroids.

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© 2017 by The Japanese Society of Internal Medicine
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