Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Successful Application of Edoxaban in the Treatment of Venous Thromboembolism Recurrence in a Patient with Non-small Cell Lung Cancer after Tumor Shrinkage
Tetsuaki ShojiHidenori MizugakiYasuyuki IkezawaMegumi FurutaYuta TakashimaHajime KikuchiHouman GoudarziHajime AsahinaJunko KikuchiEiki KikuchiJun Sakakibara-KonishiNaofumi ShinagawaIchizo TsujinoMasaharu Nishimura
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JOURNALS OPEN ACCESS

2018 Volume 57 Issue 12 Pages 1769-1772

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Abstract

This report describes the case of a 66-year-old man with non-small cell lung cancer and venous thromboembolism (VTE). Unfractionated heparin (UFH) was initially used to control VTE before chemotherapy. However, switching UFH to warfarin or edoxaban, a novel oral anticoagulant (NOAC), failed. Chemotherapy was then administered to control the tumor which was thought to have been the main cause of VTE, which had been treated by UFH. After tumor shrinkage was achieved by chemotherapy, we were able to successfully switch from UFH to edoxaban. Controlling the tumor size and activity enabled the use of edoxaban as maintenance therapy for VTE.

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© 2018 by The Japanese Society of Internal Medicine
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