Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Substantial Improvement in a Nerve Conduction Study of Lymphoma-associated Demyelinating Neuropathy Treated by Intravenous Immunoglobulin and Chemotherapy
Tomoki IemuraAkifumi ObaMasashi MatsuiChihiro ManoNorihiro KawabataYoshihito HorisawaYasuko MiyaharaMitsuru Itoh
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JOURNALS OPEN ACCESS

2018 Volume 57 Issue 23 Pages 3467-3472

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Abstract

A 64-year-old woman with lymphoma-associated demyelinating neuropathy was treated by 6 cycles of R-CHOP with intravenous immunoglobulin in the first 2 cycles. We noted substantial improvement in the findings of a nerve conduction study (NCS) after the first cycle, followed by more protracted improvement during the second to sixth cycles. The improvement of the neurological symptoms paralleled the findings of the NCS. Our case provides important information for understanding the etiology and optimization of treatments for lymphoma-associated demyelinating neuropathy.

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© 2018 by The Japanese Society of Internal Medicine
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