Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Isolated Pancreatic Myeloid Sarcoma Associated with t(8;21)/RUNX1-RUNX1T1 Rearrangement
Kenji TokunagaAyako YamamuraShikiko UenoYoshitaka KikukawaShunichiro YamaguchiMichihiro HidakaNaofumi MatsunoTatsuya KawaguchiMasao MatsuokaYutaka Okuno
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JOURNALS OPEN ACCESS

2018 Volume 57 Issue 4 Pages 563-568

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Abstract

No valid treatment for isolated myeloid sarcoma (IMS) has yet been established, and no thorough genetic examinations have been performed because of its low incidence and unique manner of development. We herein report a 34-year-old man with pancreatic IMS with t(8;21)/RUNX1-RUNX1T1 rearrangement. He was treated with high-dose cytarabine followed by allogeneic hematopoietic stem cell transplantation (allo-HSCT). This is the first report of pancreatic IMS with t(8;21). Positron emission tomography/computed tomography and genetic study are useful for the diagnosis, and allo-HSCT achieved complete remission in this patient.

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© 2018 by The Japanese Society of Internal Medicine
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