Intravascular Large B-cell Lymphoma Mimicking Hepatobiliary Infection: A Case Report and Literature Review

Ryusaku Kusunoki; Hirofumi Fujishiro; Misaki Yoshimura; Kiyoka Sawada; Shinsuke Suemitsu; Masatoshi Kataoka; Aya Fujiwara; Kousuke Tsukano; Satoshi Kotani; Satoshi Yamanouchi; Masaki Tanaka; Youichi Miyaoka; Tatsuya Miyake; Naruaki Kohge; Tomonori Imaoka; Hideyuki Ohnuma; Shunji Ishihara; Yoshikazu Kinoshita

doi:10.2169/internalmedicine.1995-18

CASE REPORTS

Intravascular Large B-cell Lymphoma Mimicking Hepatobiliary Infection: A Case Report and Literature Review

Ryusaku Kusunoki, Hirofumi Fujishiro, Misaki Yoshimura, Kiyoka Sawada, Shinsuke Suemitsu, Masatoshi Kataoka, Aya Fujiwara, Kousuke Tsukano, Satoshi Kotani, Satoshi Yamanouchi, Masaki Tanaka, Youichi Miyaoka, Tatsuya Miyake, Naruaki Kohge, Tomonori Imaoka, Hideyuki Ohnuma, Shunji Ishihara, Yoshikazu Kinoshita

Author information

Ryusaku Kusunoki
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Hirofumi Fujishiro
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Misaki Yoshimura
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Kiyoka Sawada
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Shinsuke Suemitsu
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Masatoshi Kataoka
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Aya Fujiwara
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Kousuke Tsukano
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Satoshi Kotani
Department of Endoscopy, Shimane Prefectural Central Hospital, Japan
Satoshi Yamanouchi
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Masaki Tanaka
Department of Endoscopy, Shimane Prefectural Central Hospital, Japan
Youichi Miyaoka
Department of Endoscopy, Shimane Prefectural Central Hospital, Japan
Tatsuya Miyake
Department of Hepatology, Shimane Prefectural Central Hospital, Japan
Naruaki Kohge
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Tomonori Imaoka
Department of Gastroenterology, Shimane Prefectural Central Hospital, Japan
Hideyuki Ohnuma
Department of Pathology, Shimane Prefectural Central Hospital, Japan
Shunji Ishihara
Department of Internal Medicine 2, Shimane University School of Medicine, Japan
Yoshikazu Kinoshita
Department of Internal Medicine 2, Shimane University School of Medicine, Japan

Keywords: intravascular large B-cell lymphoma, acalculous cholecystitis

JOURNAL OPEN ACCESS

2019 Volume 58 Issue 13 Pages 1885-1889

DOI https://doi.org/10.2169/internalmedicine.1995-18

Details

Abstract

Intravascular large B-cell lymphoma (IVLBCL) frequently involves the hepatobiliary system, but its clinical course and pathophysiology are still not fully known. We herein describe a case of IVLBCL mimicking acute hepatobiliary infection. An 85-year-old woman was admitted because of fever and epigastric pain, and she was diagnosed to have acute acalculous cholecystitis based on gallbladder wall thickening with fluid collection. The gallbladder swelling regressed within several days, and areas of intrahepatic hypoperfusion appeared. Inflammation continued despite treatment with antibiotics, and she died within 21 days. An autopsy examination revealed IVLBCL. IVLBCL can present as acute cholecystitis with an improvement in the imaging findings and the presence of a subsequent liver mass.

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