Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
ORIGINAL ARTICLES
Clinical Impact of Piecemeal Resection Concerning the Lateral Spread of Ampullary Adenomas
Kenjiro YamamotoAtsushi SofuniTakayoshi TsuchiyaKentaro IshiiShujiro TsujiReina TanakaRyosuke TonozukaMitsuyoshi HonjoShuntaro MukaiMitsuru FujitaYasutsugu AsaiYukitoshi MatsunamiYuichi NagakawaHiroshi YamaguchiTakao Itoi
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JOURNALS OPEN ACCESS

2019 Volume 58 Issue 7 Pages 901-906

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Abstract

Objective Endoscopic papillectomy (EP) has been recognized to be a safe and reliable treatment modality for ampullary adenomas. The purpose of this study was to determine the safety and efficacy of endoscopic piecemeal resection for laterally spreading ampullary adenomas and to compare these findings with a control population of smaller conventional ampullary tumors treated in the same time period.

Methods Between May 1999 and September 2015, 136 patients underwent EP at Tokyo Medical University hospital. A total of 125 patients underwent en bloc resection, and 11 patients underwent piecemeal resection.

Results The final pathological diagnoses were 103 adenomas, 14 carcinomas in adenomas, 4 carcinomas, and 4 hyperplasia in the en bloc resection group, versus 7 adenomas, 3 carcinomas in adenoma, and 1 carcinomas in the piecemeal resection group. A single treatment session was possible in 104 (83.2%) of the 125 patients in the en bloc resection group and in 8 (72.7%) of the 11 in the piecemeal resection group. The total resection rate including additional treatments was 98.4% in the en bloc resection group and 100% in the piecemeal resection group.

Conclusion Piecemeal resection for laterally spreading ampullary adenomas was sufficiently performed compared with en bloc resection.

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© 2019 by The Japanese Society of Internal Medicine
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