Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis
Masahiro NaganoKatsuya KobayashiMayumi Yamada-OtaniAkira KuzuyaRiki MatsumotoJiro OitaMakoto YonedaAkio IkedaRyosuke Takahashi
Author information
JOURNALS OPEN ACCESS

2019 Volume 58 Issue 8 Pages 1167-1172

Details
Abstract

Hashimoto's encephalopathy (HE) is a steroid-responsive autoimmune encephalopathy associated with Hashimoto thyroiditis. We herein report a case of HE manifesting "smoldering" limbic encephalitis with persisting symptoms and abnormalities on examinations. Although our patient experienced partial clinical remission after treatment, hippocampal hypermetabolism on [18F] fluorodeoxyglucose positron emission tomography (FDG-PET) and subclinical seizures on video electroencephalography persisted. Hypermetabolism on FDG-PET was improved by additional prednisolone therapy. Thus, as with other autoimmune limbic encephalitis cases, HE can take a course of "smoldering" encephalitis. FDG-PET and electroencephalogram findings can reflect the disease activity degree in such patients, although with certain neurophysiological and biochemical distinctions.

Information related to the author
© 2019 by The Japanese Society of Internal Medicine
Previous article Next article
feedback
Top