Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion
Yusaku KusabaShinyu IzumiJin TakasakiManabu SuzukiDaisuke KatagiriTakashi KatsunoShuichiro MatsumotoKeita SakamotoMasao HashimotoNorio OhmagariHarutaka KatanoTadaki SuzukiMasayuki HojoHaruhito Sugiyama
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JOURNALS OPEN ACCESS

2020 Volume 59 Issue 19 Pages 2405-2408

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Abstract

An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.

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© 2020 by The Japanese Society of Internal Medicine
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