Coronavirus Disease 2019 Complicated by Multiple Simultaneous Intracerebral Hemorrhages

Ryota Motoie; Masaya Akai; Takahiro Kitahara; Hisaji Imamura; Takeshi Tanabe; Katsuhiko Sarazawa; Seiichiro Takano; Hiroki Toda; Kazuto Komatsu

doi:10.2169/internalmedicine.5697-20

CASE REPORTS

Coronavirus Disease 2019 Complicated by Multiple Simultaneous Intracerebral Hemorrhages

Ryota Motoie, Masaya Akai, Takahiro Kitahara, Hisaji Imamura, Takeshi Tanabe, Katsuhiko Sarazawa, Seiichiro Takano, Hiroki Toda, Kazuto Komatsu

Author information

Ryota Motoie
Department of Neurosurgery, Japanese Red Cross Fukui Hospital, Japan
Masaya Akai
Department of Respiratory Medicine, Japanese Red Cross Fukui Hospital, Japan
Takahiro Kitahara
Department of Neurosurgery, Japanese Red Cross Fukui Hospital, Japan
Hisaji Imamura
Department of Neurology, Japanese Red Cross Fukui Hospital, Japan
Takeshi Tanabe
Department of Anesthesiology, Japanese Red Cross Fukui Hospital, Japan
Katsuhiko Sarazawa
Department of Cardiology, Japanese Red Cross Fukui Hospital, Japan
Seiichiro Takano
Department of Neurology, Japanese Red Cross Fukui Hospital, Japan
Hiroki Toda
Department of Neurosurgery, Japanese Red Cross Fukui Hospital, Japan
Kazuto Komatsu
Department of Nephrology and Urology, Japanese Red Cross Fukui Hospital, Japan

Keywords: COVID-19, SARS-CoV-2, intracerebral hemorrhage, ECMO, hypercoagulability, anticoagulant

JOURNAL OPEN ACCESS

2020 Volume 59 Issue 20 Pages 2597-2600

DOI https://doi.org/10.2169/internalmedicine.5697-20

Browse “Advance online publication” version

Details

Abstract

The relationship between coronavirus disease 2019 (COVID-19) and intracerebral hemorrhage remains unclear. We herein report a case of severe COVID-19 pneumonia complicated by multiple simultaneous intracerebral hemorrhages (MSICH). The patient died eight days after the episode of MSICH. No apparent coagulopathy was observed; however, extracorporeal membrane oxygenation and anticoagulation might have caused the occurrence of MSICH. Laboratory findings showed hypercoagulability, suggesting that thrombotic etiologies, such as sinus thrombosis or cerebral infarction, might also have caused MSICH. MSICH can occur as a fatal complication of COVID-19, and this should be considered when providing treatment.

Corresponding author

Register with J-STAGE for free!