Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Atypical Sarcoidosis Diagnosed by Massive Splenomegaly
Satomi SaitoKazuhisa KodamaTomomi KogisoYuki YamanashiMakiko TaniaiShunichi AriizumiMasakazu YamamotoKatsutoshi Tokushige
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JOURNAL OPEN ACCESS

2020 Volume 59 Issue 5 Pages 641-648

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Abstract

We examined a 22-year-old woman who was admitted to our hospital with abdominal distention. At 19 years of age, the patient presented with hepatosplenomegaly. She was examined several times in another hospital; however, the cause was unidentified. Our evaluation showed severe pancytopenia and a spleen 13×24 cm in size. The serum levels of angiotensin-converting enzyme and lysozyme were elevated. She was diagnosed with liver sarcoidosis based on non-caseating epithelioid granuloma in liver biopsy tissue. To improve the symptoms, splenectomy was performed, and her pancytopenia and symptoms improved. Sarcoidosis should be considered in cases of massive splenomegaly.

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© 2020 by The Japanese Society of Internal Medicine
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