PaO2-guided Low-dose Oxygen Therapy for Pneumatosis Cystoides Intestinalis to Prevent Acute Exacerbation of Interstitial Pneumonia

Noboru Hamada; Takafumi Yamano; Yusaku Tada; Yasuhiro Ooue; Junko Itano; Mitsunori Ishiga; Hisaaki Tanaka; Goro Kimura; Yasushi Tanimoto

doi:10.2169/internalmedicine.7064-21

CASE REPORTS

PaO₂-guided Low-dose Oxygen Therapy for Pneumatosis Cystoides Intestinalis to Prevent Acute Exacerbation of Interstitial Pneumonia

Noboru Hamada, Takafumi Yamano, Yusaku Tada, Yasuhiro Ooue, Junko Itano, Mitsunori Ishiga, Hisaaki Tanaka, Goro Kimura, Yasushi Tanimoto

Author information

Noboru Hamada
Department of Respiratory Medicine, Okayama City Hospital, Japan
Takafumi Yamano
Department of Respiratory Medicine, Okayama City Hospital, Japan
Yusaku Tada
Department of Respiratory Medicine, Okayama City Hospital, Japan
Yasuhiro Ooue
Department of Allergy and Respiratory Medicine, National Hospital Organization, Minami Okayama Medical Center, Japan
Junko Itano
Department of Allergy and Respiratory Medicine, Okayama University Hospital, Japan
Mitsunori Ishiga
Department of Allergy and Respiratory Medicine, National Hospital Organization, Minami Okayama Medical Center, Japan
Hisaaki Tanaka
Department of Allergy and Respiratory Medicine, National Hospital Organization, Minami Okayama Medical Center, Japan
Goro Kimura
Department of Allergy and Respiratory Medicine, National Hospital Organization, Minami Okayama Medical Center, Japan
Yasushi Tanimoto
Department of Allergy and Respiratory Medicine, National Hospital Organization, Minami Okayama Medical Center, Japan

Keywords: PaO₂ level, low-dose oxygen therapy, interstitial pneumonia, pneumatosis cystoides intestinalis

JOURNAL OPEN ACCESS

2021 Volume 60 Issue 19 Pages 3101-3105

DOI https://doi.org/10.2169/internalmedicine.7064-21

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Abstract

We herein report the first case of low-dose oxygen therapy for pneumatosis cystoides intestinalis (PCI) using PaO₂ as a therapeutic index to prevent acute exacerbation of interstitial pneumonia. An 86-year-old man was admitted to our hospital with abdominal distension. PCI was diagnosed by abdominal computed tomography. Low-dose oxygen therapy was started to avoid acute exacerbation of interstitial pneumonia. The oxygen dose was adjusted so that the PaO₂ value was approximately 100 mmHg. After seven days of treatment, the colon gas had disappeared, and no acute exacerbation of interstitial pneumonia was observed. A PaO₂ value around 100 mmHg is effective for PCI without inducing acute exacerbation of interstitial pneumonia.

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