Severe Anemia Caused by Gastric Antral Vascular Ectasia and Autoimmune Gastritis

Kazuhiro Ota; Yosuke Mori; Hironori Tanaka; Takahiro Murata; Taro Iwatsubo; Shimpei Kawaguchi; Yuichi Kojima; Noriyuki Nakajima; Akitoshi Hakoda; Noriaki Sugawara; Toshihisa Takeuchi; Kazuhide Higuchi

doi:10.2169/internalmedicine.9225-21

CASE REPORTS

Severe Anemia Caused by Gastric Antral Vascular Ectasia and Autoimmune Gastritis

Kazuhiro Ota, Yosuke Mori, Hironori Tanaka, Takahiro Murata, Taro Iwatsubo, Shimpei Kawaguchi, Yuichi Kojima, Noriyuki Nakajima, Akitoshi Hakoda, Noriaki Sugawara, Toshihisa Takeuchi, Kazuhide Higuchi

Author information

Kazuhiro Ota
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Yosuke Mori
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Hironori Tanaka
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Takahiro Murata
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Taro Iwatsubo
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Shimpei Kawaguchi
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Yuichi Kojima
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Noriyuki Nakajima
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Akitoshi Hakoda
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Noriaki Sugawara
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Toshihisa Takeuchi
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan
Kazuhide Higuchi
Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan

Keywords: iron deficiency, vitamin B₁₂ deficiency, gastric antral vascular ectasia, autoimmune gastritis, hypergastrinemia, severe anemia

JOURNAL OPEN ACCESS

2022 Volume 61 Issue 19 Pages 2873-2876

DOI https://doi.org/10.2169/internalmedicine.9225-21

Browse “Advance online publication” version

Details

Abstract

An 80-year-old man presented to our hospital with general fatigue on exertion that had gradually worsened over 6 months. His blood test revealed severe anemia, and gastroscopy revealed findings consistent with gastric antral vascular ectasia (GAVE) and autoimmune gastritis. We diagnosed the patient with severe anemia caused by GAVE and autoimmune gastritis. The present case suggested that GAVE is triggered by autoimmune gastritis, and the mechanism is likely related to hypergastrinemia. The reporting of this rare case may help elucidate the cause of GAVE, which is currently unknown.

Corresponding author

Register with J-STAGE for free!