Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19

Norihito Omote; Yoshihiro Kanemitsu; Takahiro Inoue; Toshiyuki Yonezawa; Takuji Ichihashi; Yuichiro Shindo; Koji Sakamoto; Akira Ando; Atsushi Suzuki; Akio Niimi; Satoru Ito; Kazuyoshi Imaizumi; Naozumi Hashimoto

doi:10.2169/internalmedicine.8163-21

CASE REPORTS

Successful Treatment with High-dose Steroids for Acute Exacerbation of Idiopathic Pulmonary Fibrosis Triggered by COVID-19

Norihito Omote, Yoshihiro Kanemitsu, Takahiro Inoue, Toshiyuki Yonezawa, Takuji Ichihashi, Yuichiro Shindo, Koji Sakamoto, Akira Ando, Atsushi Suzuki, Akio Niimi, Satoru Ito, Kazuyoshi Imaizumi, Naozumi Hashimoto

著者情報

Norihito Omote
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan
Department of Internal Medicine, Aichi Prefectural Hospital, Japan
Yoshihiro Kanemitsu
Department of Internal Medicine, Aichi Prefectural Hospital, Japan
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Japan
Takahiro Inoue
Department of Internal Medicine, Aichi Prefectural Hospital, Japan
Department of Respiratory Medicine, Fujita Health University School of Medicine, Japan
Toshiyuki Yonezawa
Department of Internal Medicine, Aichi Prefectural Hospital, Japan
Department of Respiratory Medicine and Allergology, Aichi Medical University, Japan
Takuji Ichihashi
Department of Internal Medicine, Aichi Prefectural Hospital, Japan
Yuichiro Shindo
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan
Department of Internal Medicine, Aichi Prefectural Hospital, Japan
Koji Sakamoto
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan
Akira Ando
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan
Atsushi Suzuki
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan
Akio Niimi
Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Japan
Satoru Ito
Department of Respiratory Medicine and Allergology, Aichi Medical University, Japan
Kazuyoshi Imaizumi
Department of Respiratory Medicine, Fujita Health University School of Medicine, Japan
Naozumi Hashimoto
Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan

キーワード: COVID-19, acute exacerbation, idiopathic pulmonary fibrosis, high-dose steroid, case report

ジャーナルオープンアクセス

2022 年 61 巻 2 号 p. 233-236

DOI https://doi.org/10.2169/internalmedicine.8163-21

Browse “Advance online publication” version

詳細

抄録

We herein report a case of acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) triggered by COVID-19. An 87-year-old woman tested positive for COVID-19 on a polymerase chain reaction test, and computed tomography revealed ground-glass opacity (GGO) superimposed on a background pattern consistent with usual interstitial pneumonia. Considering these data, we diagnosed her with AE-IPF. She experienced worsening of dyspnea and expansion of the GGO. Therefore, we introduced high-dose steroids (methylprednisolone 250 mg/day for 3 days). After the treatment, the pulmonary infiltrates improved. She was discharged from our hospital without severe disability. High-dose steroids can be a viable treatment option for AE-IPF triggered by COVID-19.

責任著者(Corresponding author)

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