Two Cases with Isolated Splenic Sarcoidosis Diagnosed by an Ultrasound-guided Fine-needle Aspiration Biopsy

Aya Tanimoto; Michihiko Shibata; Yuichi Honma; Kahori Morino; Masashi Kusanaga; Shintaro Abe; Masaru Harada

doi:10.2169/internalmedicine.0409-22

CASE REPORTS

Two Cases with Isolated Splenic Sarcoidosis Diagnosed by an Ultrasound-guided Fine-needle Aspiration Biopsy

Aya Tanimoto, Michihiko Shibata, Yuichi Honma, Kahori Morino, Masashi Kusanaga, Shintaro Abe, Masaru Harada

Author information

Aya Tanimoto
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
Michihiko Shibata
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
Yuichi Honma
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
Kahori Morino
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
Masashi Kusanaga
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
Shintaro Abe
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
Masaru Harada
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan

Keywords: isolated splenic sarcoidosis, ultrasonography, fine-needle aspiration biopsy

JOURNAL OPEN ACCESS

2023 Volume 62 Issue 14 Pages 2077-2083

DOI https://doi.org/10.2169/internalmedicine.0409-22

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Abstract

Asymptomatic splenic nodules were detected incidentally in two middle-aged women at an annual checkup. They showed no abnormalities on laboratory tests, but imaging studies revealed splenic nodules. No other localized lesions were found. Splenic nodules were hypoechoic on ultrasonography (US), hypovascular on contrast-enhanced computed tomography, and showed a low intensity on T2-weighted magnetic resonance imaging. We performed US-guided percutaneous aspiration biopsies using 21-gauge needles without complications, including bleeding. Pathological specimens showed noncaseating granulomas, so both patients were diagnosed with isolated splenic sarcoidosis. A US-guided fine-needle aspiration biopsy is a safe and useful method for diagnosing splenic nodules.

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