Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Successful Discontinuation of Glucocorticoid Treatment after Administration of a Calcineurin Inhibitor for Nephrotic Syndrome in a Patient with Lupus Nephritis
Masato SawamuraNaoki SawaDaisuke IkumaYuki ObaMasayuki YamanouchiAkinari SekineHiroki MizunoEiko HasegawaTatsuya SuwabeJunichi HoshinoKei KonoKeiichi KinowakiKenichi OhashiYoshifumi Ubara
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ジャーナル オープンアクセス

2023 年 62 巻 7 号 p. 1037-1041

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Systemic lupus erythematosus was diagnosed in a patient at 43 years old. When proteinuria recurred at 57 years old, the first kidney biopsy was performed, and class IV-G (A) +V lupus nephritis was diagnosed. The prednisolone dose was increased to 40 mg/day, and cyclosporine A was introduced. After 1 year, proteinuria had decreased to 0.1 g/day. Prednisolone was discontinued three years later, and cyclosporine A was continued. Thereafter, proteinuria did not reoccur. At 67 years old, a second kidney biopsy showed complete remission of lupus nephritis. Cyclosporine A enabled permanent discontinuation of glucocorticoids in a patient with lupus nephritis.

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© 2023 by The Japanese Society of Internal Medicine
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