Fasciolosis Reinfection in Japan

Kumiko Akiyoshi; Mio Kokubo-Tanaka; Shuichiro Yamauchi; Keisuke Yonezu; Ichitaro Abe; Katsunori Tawara; Shotaro Saito; Hidekazu Kondo; Tomoko Fukuda; Akira Fukui; Hidefumi Akioka; Tetsuji Shinohara; Yasushi Teshima; Kunio Yufu; Nobuyuki Shimono; Yusuke Mizuno; Takao Irie; Ayako Yoshida; Naohiko Takahashi; Haruhiko Maruyama

doi:10.2169/internalmedicine.5818-25

CASE REPORTS

Fasciolosis Reinfection in Japan

Kumiko Akiyoshi, Mio Kokubo-Tanaka, Shuichiro Yamauchi, Keisuke Yonezu, Ichitaro Abe, Katsunori Tawara, Shotaro Saito, Hidekazu Kondo, Tomoko Fukuda, Akira Fukui, Hidefumi Akioka, Tetsuji Shinohara, Yasushi Teshima, Kunio Yufu, Nobuyuki Shimono, Yusuke Mizuno, Takao Irie, Ayako Yoshida, Naohiko Takahashi, Haruhiko Maruyama

Author information

Kumiko Akiyoshi
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Mio Kokubo-Tanaka
Department of Infectious Diseases, Division of Parasitology, Faculty of Medicine, University of Miyazaki, Japan
Shuichiro Yamauchi
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Keisuke Yonezu
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Ichitaro Abe
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Katsunori Tawara
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Shotaro Saito
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Hidekazu Kondo
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Tomoko Fukuda
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Akira Fukui
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Hidefumi Akioka
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Tetsuji Shinohara
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Yasushi Teshima
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Kunio Yufu
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Nobuyuki Shimono
Center for the Study of Global Infection, Kyushu University Hospital, Japan
Yusuke Mizuno
Laboratory of Veterinary Parasitic Diseases, Department of Veterinary Sciences, Faculty of Agriculture, University of Miyazaki, Japan
Takao Irie
Laboratory of Veterinary Parasitic Diseases, Department of Veterinary Sciences, Faculty of Agriculture, University of Miyazaki, Japan
Center for Animal Disease Control, University of Miyazaki, Japan
Ayako Yoshida
Laboratory of Veterinary Parasitic Diseases, Department of Veterinary Sciences, Faculty of Agriculture, University of Miyazaki, Japan
Center for Animal Disease Control, University of Miyazaki, Japan
Naohiko Takahashi
Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Japan
Haruhiko Maruyama
Department of Infectious Diseases, Division of Parasitology, Faculty of Medicine, University of Miyazaki, Japan
Center for Animal Disease Control, University of Miyazaki, Japan

Keywords: Fasciola, large liver fluke, parasitic liver diseases, eosinophilia, prevention

JOURNAL OPEN ACCESS

2026 Volume 65 Issue 6 Pages 921-925

DOI https://doi.org/10.2169/internalmedicine.5818-25

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Details

Abstract

Fasciolosis is a major cause of food-borne parasitic zoonosis. It primarily affects ruminants but also infects humans. Clinically, it is characterized by abnormal liver images with prominent eosinophilia. We herein report a 77-year-old Japanese livestock farmer, who experienced fasciolosis reinfection. Environmental investigation of his residence revealed that both intermediate host snails and sika deer, a natural final host, inhabited his house. In addition, cattle were infected with Fasciola. Based on these findings, we concluded that his work place was accidentally contaminated with Fasciola metacercariae.

Corresponding author

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