Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Aortic Mural Thrombus in the Non-Atherosclerotic Aorta of Patients with Multiple Hypercoagulable Factors
Takeshi YagyuMaiko NaitoMasahiro KumadaTsutomu Nakagawa
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JOURNAL OPEN ACCESS Advance online publication

Article ID: 0691-17


An aortic mural thrombus (AMT) on a non-atherosclerotic wall is a rare but important cause of arterial thromboembolism. We herein report two cases of AMT in the thoracic aorta. Both showed multiple hypercoagulable factors (case 1: protein S deficiency and positive finding of anti-cardiolipin antibody; case 2: protein C deficiency, gastric cancer, and cisplatin-based chemotherapy) and were successfully treated with anticoagulation. Hypercoagulable states, including malignancy, can influence the formation of AMT; therefore, the accurate assessment of a hypercoagulable condition is necessary when we encounter patients with AMT.

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© 2019 by The Japanese Society of Internal Medicine